With the implementation of HGP (Human Genome Project, HGP), life science has entered the post-genomic era, hundreds of different types of databases have been developed according to the exponential growth of nucleic acid, protein sequence and structure data. These distributed, autonomous and heterogeneous databases resulted in great difficulties in sharing and integrating data for researchers.
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Since its starting implementation in the early 1990s, the Human Genome Project (HGP) has got tremendous achievements under the united efforts of scientists all over the world. Meanwhile the Genomics and Proteomics have achieved great development. Nowadays, with the unprecedented growth of biological information, human beings obtain a great deal of sequence information concerning amino
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